Dapoxetine Hydrochloride Cas:129938-20-1
Dapoxetine hydrochloride is chemically known as (S)-N, n-dimethyl-3 -(naphthyl-1-oxy) -phenylpropylamino-hydrochloride. Dapoxetine hydrochloride has similar pharmacological effects to other SSRIs. Dapoxetine was originally investigated as an antidepressant, but unlike other SSRIs, Dapoxetine's pharmacokinetics have shown rapid oral absorption, short half-life, and rapid excretion, making it a suitable drug for the treatment of premature ejaculatory use.
Properties: Dapoxetine hydrochloride is white to white powder; It is easily soluble in methanol and ethanol, slightly soluble in dichloroethane, and almost insoluble in water.
Dapoxetine hydrochloride is a BCSII compound, and poor solubility is the key factor affecting the difference of clinical efficacy.
Dapoxetine hydrochloride exists in a variety of crystal forms, and the solubility of different crystal forms is very different, and there is phase and transformation between the crystal forms.
Uses: Dapoxetine hydrochloride is a selective serotonin reuptake inhibitor (SSRI).
Application: Dapoxetine impurities are organic synthesis intermediates and pharmaceutical intermediates, which can be used in laboratory research and development process and chemical pharmaceutical synthesis process, mainly as API Dapoxetine hydrochloride intermediates. Bioactive DapoxetineHCl(LY-210448) is a short-acting, novel selective serotonin reuptake inhibitor.
