HCG (Human Chorionic Gonadotropin) 5000 IU is commonly used for medical purposes such as **fertility treatment, hormone regulation or male hypogonadism**. The following is a detailed **use guide**, including **injection method, dosage recommendations, storage and precautions**.
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## **1. Preparation before use**
### **① Drug inspection**
- **HCG lyophilized powder**: 5000 IU/bottle (usually white powder).
- **Attached solvent**: 1 mL sterile water for injection (or saline).
- **Syringe**: 1 mL insulin syringe (with a fine needle, such as 29G-31G).
- **Disinfectants**: alcohol cotton pads, sterile gauze.
### **② Storage conditions**
- **Undissolved lyophilized powder**: **2-8°C refrigerated** (do not freeze).
- **Dissolved drug solution**: **Refrigerated and used within 24 hours** (some brands allow 48 hours).
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## **2. Dissolve HCG lyophilized powder**
### **Steps**
1. **Wash hands and disinfect**: Wipe the rubber stopper of the vial (lyophilized powder + solvent) with an alcohol pad.
2. **Draw out solvent**:
- Draw out **1 mL of sterile water for injection** (or with solvent) with a syringe.
3. **Inject solvent**:
- Slowly inject the solvent** into the lyophilized powder vial** (avoid direct impact on the powder).
4. **Dissolve the drug**:
- **Gently rotate the vial** (do not shake) until it is completely dissolved (the solution should be clear and free of particles).
> **⚠️ Note**: Violent shaking may cause protein denaturation and reduce drug efficacy.
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## **3. Injection method (subcutaneous/intramuscular injection)**
HCG is usually injected **subcutaneously (abdomen/thigh)** or **intramuscularly (buttocks/thighs)**, depending on the doctor's advice.
### **① Subcutaneous injection (recommended)**
- **Suitable sites**: abdomen (5 cm outside the navel), front of thigh.
- **Steps**:
1. **Disinfect the skin**: Wipe the injection site with an alcohol cotton pad.
2. **Pinch the skin**: Gently pinch the subcutaneous fat layer with the thumb and index finger.
3. **Insert the needle at 45° or 90°** (depending on the thickness of the fat).
4. **Slowly push the drug solution**, stay for 5 seconds after the injection is completed and then remove the needle.
### **② Intramuscular injection (less commonly used)**
- **Suitable sites**: upper outer side of the buttocks (gluteus maximus) or outer thigh.
- **Steps**:
1. **Disinfect the skin**.
2. **Quickly insert the needle vertically** (90°).
3. **Slowly push the drug**, press with a cotton pad after removing the needle.
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## **4. Dosage recommendations**
### **HCG 5000 IU usage plans for different purposes**
| **Purpose** | **Recommended dose** | **Injection frequency** | **Remarks** |
|----------|-------------|-------------|----------|
| **Ovulation induction (female)** | 5000-10000 IU **Single injection** | 1 time (doctor's guidance) | Usually injected after follicles mature |
| **Luteal support (female)** | 1500-5000 IU **1-2 times per week** | According to doctor's plan | Used to maintain hormones in early pregnancy |
| **Treatment of low testosterone in men** | 500-2000 IU **2-3 times per week** | Long-term (adjust as needed) | Can be used in combination with other hormone treatments |
| **Cryptorchiosis (children)** | 1000-5000 IU **2 times per week** | Short-term (4-6 weeks) | Must strictly follow the doctor's instructions |
> **⚠️ Important**: The specific dosage must be adjusted by the doctor according to personal circumstances!
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## **5. Precautions**
✅ **Correct operation**
- Check whether the liquid is clear before each injection (if it is turbid or precipitated, it cannot be used).
- Rotate the injection site to avoid local nodules.
❌ **Avoid mistakes**
- **Do not inject intravenously** (may cause serious adverse reactions).
- **Do not reuse needles** (avoid infection or contamination of the liquid).
⚠️ **Side effect monitoring**
- **Common**: redness and swelling at the injection site, mild headache, mood swings.
- **Serious (rare)**: Ovarian hyperstimulation syndrome (OHSS, female), risk of thrombosis.
→ If severe abdominal pain or difficulty breathing occurs, seek medical attention immediately!
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## **6. Frequently Asked Questions**
### **Q1: Can HCG 5000 IU be used in divided doses? **
- **Yes**, but it must be refrigerated within **24 hours after dissolution**, and ensure aseptic operation.
- For example: after dissolution, extract 0.5 mL (2500 IU) for injection, and the remaining 0.5 mL is refrigerated for use the next day.
### **Q2: What if there is no accompanying solvent? **
- **Sterile water for injection can be used as a substitute** (available in pharmacies), but avoid using ordinary saline (unless the instructions allow).
### **Q3: Can HCG help lose weight? **
- **Not recommended**! Although some weight loss programs abuse HCG, there is no scientific basis and it may cause serious side effects.
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## **Summary**
- **Dissolution method**: 5000 IU + 1 mL sterile water for injection, gently rotate to dissolve.
- **Injection method**: subcutaneous (abdomen/thigh) or intramuscular injection (buttocks).
- **Dosage**: Strictly follow the doctor's instructions, different uses vary greatly.
- **Storage**: Refrigerate if not dissolved, use within 24 hours after dissolution.
**⚠️Important reminder**: HCG is a prescription drug and must be used under the guidance of a doctor. The dosage cannot be adjusted at your own discretion!
