Tirzepatide comes as a solution (liquid) in a pre-filled pen to be injected subcutaneously (under the skin). It is usually given once a week with or without meals at any time of day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use tirzepatide exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Your doctor will probably start you on a low dose of tirzepatide and gradually increase your dose, not more than once every 4 weeks.
You may change the day of the week you inject tirzepatide as long as at least 3 days have passed between doses.
You may administer insulin in the same area as tirzepatide but they should not be given right next to each other. Also, you should not mix tirzepatide and insulin in the same injection.
Tirzepatide controls type 2 diabetes but does not cure it. It may take 4 weeks or longer before you feel the full benefit of tirzepatide. Continue to take tirzepatide even if you feel well. Do not stop taking tirzepatide without talking to your doctor.
Tirzepatide can be injected in the abdomen, thigh or upper arm. Rotate injection sites with each dose.
Recommended dose
1. The recommended starting dose of Tirzepatide is 2.5 mg subcutaneously injected once a week. The 2.5 mg dose is used at the beginning of treatment and is not used for blood glucose control.
After 2 or 4 weeks, the dose was increased to 5 mg and injected subcutaneously once a week.
3. If additional blood sugar control is needed, increase the dose in 2.5 mg increments at least 4 weeks after the current dose.
4. The maximum dose of Tirzepatide is 15 mg, given subcutaneously once a week.
5. If a dose is missed, instruct the patient to use Tirzepatide as soon as possible within 4 days (96 hours) of the missed dose. If it is more than 4 days, skip the missed dose and use the next dose on a regularly scheduled date, and resume their regular once-a-week dosing schedule after that.
6, if necessary, the weekly dosing date can be changed, as long as the time interval between dosing is at least 3 days (72 hours).
