Propionyl Chloride Cas:79-03-8
What is propanoyl chloride used for? Propanoyl chloride is an organic compound that is widely used in the production of pharmaceuticals, agrochemicals, and plastics. In the pharmaceutical industry, propanoyl chloride is commonly used as a key intermediate in the synthesis of various drugs,...

What is propanoyl chloride used for?
Propanoyl chloride is an organic compound that is widely used in the production of pharmaceuticals, agrochemicals, and plastics.
In the pharmaceutical industry, propanoyl chloride is commonly used as a key intermediate in the synthesis of various drugs, including painkillers and anti-inflammatory agents. It is also used in the production of chemicals that are commonly found in sunscreen, insect repellent, and fragrance products.
Propanoyl chloride is also used extensively in the agrochemical industry. It is an important intermediate in the production of various herbicides, insecticides, and fungicides. It plays a vital role in enhancing crop productivity and protecting plants from pests and diseases.
Furthermore, propanoyl chloride is used in the production of plastics and polymers. It is used as a reagent in the synthesis of acylating agents, which are used to modify the properties of plastics, making them more durable, heat-resistant, and resistant to chemicals.
Overall, the use of propanoyl chloride has significant benefits to society. Its wide range of applications plays a vital role in the production of high-quality products that improve our lives and contribute to the growth and development of various industries.
How do you get Propionyl chloride?
Propionyl chloride can be obtained through a synthesis reaction between propionic acid and thionyl chloride. This process involves the addition of thionyl chloride to propionic acid under carefully controlled conditions, resulting in the formation of propionyl chloride and sulfur dioxide as byproducts.
Another method for obtaining propionyl chloride involves the reaction of propionic acid with phosphorus pentachloride. This reaction also requires careful control of the reaction conditions, including the use of anhydrous solvents and low temperatures, to ensure the safety of the reaction.
It is important to note that both of these methods require careful handling, as propionyl chloride is a highly reactive and potentially dangerous substance. Proper safety procedures, including the use of protective equipment and ventilation, should be followed to ensure the safety of those involved in the production and handling of this chemical.
Overall, with proper care and attention to safety measures, propionyl chloride can be produced using a variety of methods, allowing for its use in a range of industrial applications.
What is the functional group in propanoyl chloride?
The functional group in propanoyl chloride is the acyl chloride group, which consists of a carbonyl group (C=O) and a chlorine atom bonded to the adjacent carbon atom. This functional group is commonly used in organic chemistry for acylation reactions to introduce acyl groups into organic compounds. Despite its reactivity and potential hazards, propanoyl chloride plays an essential role in the synthesis of many drugs, dyes, and other organic compounds, making it a valuable tool for researchers in the field.
What are the physical properties of propionyl chloride?
Propionyl chloride is a colorless and flammable liquid with a pungent odor. It has a formula of C3H5ClO and a molecular weight of 92.54 g/mol. The physical properties of propionyl chloride include a boiling point of 77°C, a melting point of -94°C, and a density of 1.078 g/cm³ at 20 °C.
Propionyl chloride is highly soluble in organic solvents such as benzene, chloroform, and ether but is immiscible with water. It reacts vigorously with water, producing hydrochloric acid and propionic acid, which can release toxic fumes.
Propionyl chloride is a reactive compound and can undergo numerous chemical reactions. It can react with alcohols, amines, and other compounds containing an active hydrogen atom to form esters or amides, respectively. Additionally, it can react with water to form propionic acid and hydrochloric acid. Propionyl chloride can also undergo substitution reactions with nucleophiles such as ammonia and hydroxide ions.
In summary, propionyl chloride is a colorless, flammable liquid with a pungent odor. It has a low melting and boiling point and is soluble in organic solvents. This compound is highly reactive and can undergo various chemical reactions, making it an essential intermediate in the production of pharmaceuticals, agrochemicals, and fragrances.







