CAS 62-44-2 Phenacetin To Sell
Phenacetin is white crystalline solid at room temperature, melting point about 134℃, is a antipyretic, analgesic drug.
CAS 62-44-2 Phenacetin to sell
Melting point 133-136°C(lit.)
Boiling point 132°C/4mmHg
Density 1.1248(roughestimate)
Refractive index 1.5710
Flash point 2 ° C
Storage conditions Sealedindry RoomTemperature
Solubility Chloroform(Slightly),Methanol(Slightly) methanol
Morphology powder
Acidity coefficient (pKa)pKa2.2(H2O)(Uncertain); 3.5 (aqueousacetone) (all)
Color White
Water solubility 0.076g/100mL
Principle of action
The mild analgesic effect of phenacetin can generally be maintained for 3-4 hours; The synergistic effect with salicylic acid enhances the analgesic effect. Clinically, it is mainly used for antipyretic analgesia in small animals. This product is also one of the components of APC tablets. Internal process: It is easy to absorb when taken internally, and the effect begins to appear 20-30 minutes after taking. Lasting 5-6 hours, after absorption of phenacetin most of the rapid deethyl in the liver to acetaminophen (paracetamol), showing antipyretic, analgesic effects. Subsequently, it was mainly eliminated from urine in the form of combination; A small portion is deacetylated to produce p-amphenethers, which change hemoglobin to methemoglobin and thus exhibit the cyanosis toxicity of phenacetin.
