
Lidocaine
Lidocaine hcl in low doses can promote outflow of K+ in cardiomyocytes, reduce myocardial autonomy, and has antiarrhythmic effects.
Product Profile:
Product name | Lidocaine Hcl |
Other name | L-Caine |
CAS register number | 137-58-6 |
EINECS | 205-302-8 |
Molecular formula | C14H22N2O |
Molecular weight | 234.34 |
Appearance | White crystalline powder |
Melting point | 66-69°C |
Assay | 99.9% |

Lidocaine hcl is a local anesthetic and antiarrhythmic drug. Used for infiltration anesthesia, epidural anesthesia, surface anesthesia (including in the thoracoscopy or abdominal surgery for mucosal anesthesia) and nerve conduction block.
Lidocaine hcl is an amide local anesthetic. With the dose increased, the role or toxicity increased, there is an anti-convulsive effect with sub-poisoning plasma concentration; Blood concentration of more than 5μg • ml-1 can occur convulsions.
Lidocaine hcl in low doses can promote outflow of K+ in cardiomyocytes, reduce myocardial autonomy, and has antiarrhythmic effects.
The role of lidocaine includes:
Treatment of arrhythmias, mainly ventricular arrhythmias;
2. Clinical anesthetics. There are two main effects of lidocaine: the first is to treat arrhythmias, and the second is anesthesia. Lidocaine is an anti-arrhythmic drug used by cardiologists, mainly for the treatment of ventricular arrhythmias that we call ventricular origin. Of course this is a very professional question. Generally, in our clinical patients, such as after myocardial infarction, ventricular tachycardia or obvious premature beats, we can apply lidocaine according to the situation. Then the second role of lidocaine is for local anesthesia. We are now doing some punctures, or when doing some minor operations, we need local anesthesia. At this time, we need to inject a part of lidocaine subcutaneously, and then perform puncture or Cut and so on. At this time, lidocaine, as a very commonly used anesthetic, will make you feel no particular discomfort during the entire operation or operation. Therefore, lidocaine has two main functions: the first is antiarrhythmic, and the second is used as a local anesthetic.
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