Metformin Cas:657-24-9
Metformin is the first-line and whole-course drug for the treatment of type 2 diabetes. It mainly reduces fasting and postprandial hyperglycemia by increasing insulin sensitivity of peripheral tissues such as muscle and fat, increasing glucose uptake and utilization, promoting anaerobic glycolysis of sugar, inhibiting liver glycoconogenesis, reducing liver sugar output, and inhibiting the uptake of glucose by intestinal wall cells. In addition, metformin also has a weight loss effect, and can inhibit the biosynthesis and storage of cholesterol, reduce the level of triglyceride and total cholesterol, improve the function of vascular endothelial cells, increase blood flow, especially for obese or overweight type 2 diabetes patients, prevent the occurrence and development of diabetic macrovascular complications, reduce the incidence of cardiovascular events.
What is the major side effect of metformin?
Metformin is a medication commonly prescribed for people with type 2 diabetes. It is known to be one of the most effective treatments for managing blood sugar levels and can also help with weight loss. However, like all medications, metformin does have potential side effects.
Thankfully, the most common side effect of metformin is generally mild and can be easily managed with some simple lifestyle changes. The most common side effect of metformin is gastrointestinal upset. This can manifest in the form of diarrhea, nausea, vomiting, or abdominal discomfort. However, these symptoms usually subside within a few days or weeks of starting the medication.
In rare cases, metformin can also cause a serious complication called lactic acidosis. This occurs when there is a buildup of lactic acid in the blood, which can be life-threatening. However, this is a very rare side effect and typically only occurs in people with kidney or liver problems, or those who take high doses of the medication.
Overall, metformin is a relatively safe medication with a low risk of serious side effects. For most people with type 2 diabetes, the benefits of metformin greatly outweigh any potential risks. If you are experiencing any side effects from metformin, be sure to speak with your doctor, who can offer advice and guidance on how to manage them.
Why do doctors no longer prescribe metformin?
There is no evidence to suggest that doctors are no longer prescribing metformin, a common medication used to treat type 2 diabetes. In fact, metformin is often recommended as the first line of treatment for this condition, due to its effectiveness in reducing blood sugar levels and improving insulin sensitivity.
Metformin works by reducing the amount of glucose released by the liver and increasing the body's response to insulin. It has been shown to lower the risk of heart disease and improve overall health outcomes in people with diabetes.
There are a few rare cases where metformin may not be recommended, such as in individuals with kidney or liver disease. However, in most cases, metformin is a safe and effective medication that is prescribed by doctors regularly.
It is important for individuals with type 2 diabetes to work with their healthcare team to determine the best treatment plan for their specific needs. This may include lifestyle changes, such as a healthy diet and exercise, as well as medication like metformin. By working together, individuals with diabetes can effectively manage their condition and improve their overall health and well-being.
Is it safe to take metformin daily?
Yes, it is generally safe to take metformin daily when prescribed by a doctor and taken as directed. Metformin is a medication commonly used to treat type 2 diabetes and is considered a first-line treatment option due to its effectiveness and safety profile.
Metformin works by reducing the amount of glucose produced by the liver and improving the body's sensitivity to insulin. This can help regulate blood sugar levels and prevent complications associated with diabetes, such as heart disease, nerve damage, and kidney damage.
Like any medication, metformin can cause side effects, but they usually subside within a few weeks of starting the medication. Common side effects include nausea, diarrhea, abdominal discomfort, and a metallic taste in the mouth. In rare cases, metformin can cause a serious condition called lactic acidosis, but this is more likely to occur in individuals with liver or kidney problems.
It is important to take metformin as prescribed and to keep regular appointments with your doctor to ensure that the medication is working effectively and to monitor for any potential side effects. Additionally, maintaining a healthy diet and regular exercise can help improve the effectiveness of metformin and manage blood sugar levels.
Overall, with proper use and monitoring, metformin is a safe and effective medication for treating type 2 diabetes.





