Crizotinib Cas:877399-52-5
Crizotinib (XalkoriR), whose chemical name is 3-[(R)-1-(2, 6-dichloro-3-fluorophenyl) ethoxy]-5-[1-(piperidine-4-yl) -1H-pyrazole-4-yl]Chemicalbook pyridine-2-amine, is a white to light yellow powder. Its primary role is in the treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC) patients with anaplastic lymphoma kinase (ALK) positive as determined by SFDA-approved assays.
Introduction
We have crizotinib cas 877399 52 5 for sale. This product is known by several names including Crizotinib, Xalkori and 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1 -piperidin-4-ylpyrazol-4-yl)pyridin-2-amine, etc. Its molecular formula is C21H22Cl2FN5O, its density is 1.5±0.1 g/cm3, and its boiling point is 599.2±50.0 °C at 760 mmHg. It is a white or pale yellow powder. This product is generally used for the treatment of anaplastic lymphoma or metastatic non-small cell lung cancer. This product must be used under the guidance of specific professional and technical personnel in medical institutions.
This is a drug developed by Pfizer for the targeted therapy of non-small cell lung cancer. It was approved in the United States in August 2011, and was written into the international lung cancer treatment guidelines at the end of the year as a first-line drug for ALK-positive patients. At the same time, the use of fluorescence in situ hybridization (FISH)-VysisALKBreakApartFISHProbeKit genetic diagnosis method will help to identify patients who can benefit from crizotinib treatment.
Name: Crizotinib （crizotinib cas 877399 52 5 for sale）
Molecular Formula: C21H22Cl2FN5O
EINECS:638-814-9
